Cell Signaling & Stem Cell-Mediated Tissue Repair
Using the awesome regenerative powers of the planarian flatworm — which can regenerate any and all tissues, even brain! — our lab investigates the signals that initiate and regulate regeneration. Planarians are remarkable in that they can regenerate an entire worm from just a tiny fragment of the original. This allows us to study how all the many different activities (cell migration, cell division, gene regulation, cell-cell communication, even cell death) are coordinated across thousands of cells.
Our research is focused on signaling pathways: reactive oxygen species (ROS) signaling that regulates the induction of new tissue growth, and the planar cell polarity (PCP) pathway that regulates the termination of neural growth. In partnership with our physics and engineering collaborators, we also investigate the possible use of quantum phenomena — such as changes in radical pair recombination rates by magnetic fields — to manipulate adult stem cell activity in vivo. Although our lab does basic (not translational) research, our work aims at supporting the development of future therapies in cancer and regenerative medicine.
Research Opportunities
▶We have openings for talented, self-motivated students wishing to pursue a Ph.D. degree in biomedical sciences.
▶We are not accepting undergraduate applications at this time.
Letters of RecommendationFunding Sources

CAREER AWARD
EAGER / RCN

Presidential Innovation
Professorship / FRACAA

Research Enhancement
Award (R15)
Dr. Beane's Courses
BIOS 5740
Developmental Biology
Spring (alternating)
BIOS 5970
Methods and Concepts in Biology
Spring (alternating)
BIOS 1610
Molecular & Cellular Biology
Spring
BIOS 5750
Stem Cells and Regeneration (Capstone)
Summer
Beane Lab News
Congratulations to graduate students Rae Daun Miller, M.A. and Jana Vučković, M.S. who graduated today! We will miss having Rae Daun in the lab, but we wish her the best in her next endeavours. Fortunately, it is not goodbye to Jana, as she intends to return to the lab to finish her doctoral degree. We can't wait to see what success she will have in her research pursuits!
Please help us welcome our newest lab member, undergraduate student Joshua McKissic, who will be taking on the role of Animal Care Technician (worm-washer). Welcome to the Beane nation!
The Beane lab welcomes Mattawan High School's AP Biology students who will visit the lab today for a "Planarian Regeneration" research demo.
Please help us welcome the lab's newest M.S., Jana Vučković, who just successfully defended her masters thesis. Congratulations, Jana!
Congratulations to graduate student, Jana Vučković and our collaborators at the University of Calgary whose paper with Wendy titled: "Verification of radical pair mechanism predictions for weak magnetic field effects on superoxide in planarians" was pre-printed in bioRxiv. Check it out: https://shorturl.at/C0Z84
Everyone, please welcome our new Lab Manager Jacqueline Greene! We are very happy to have Jacqueline, who previously completed her LHC Honors thesis in our lab, back in the group!
Please help us welcome the lab's newest Ph.D., Dr. Samantha Hack, who just successfully defended her doctoral dissertation. Congratulations, Sam! Much celebrating to follow.
Congratulations to undergraduate Caitlin Nolff who graduated today with Honors! We will miss having you in the lab, but look forward to hearing about all your new adventures.
Beane lab alumna Isabela Stemple (née Giorgetti de Carvalho) has been featured in an article by the WMU Alumni Association. We're so glad her accomplishments are being highlighted! Check it out: https://shorturl.at/hmMS9
Congratulations to Beane nation member Dr. Luke Kinsey and our collaborator Dr. Kelly Ai-Sun Tseng whose article with Wendy titled: "Accelerating an integrative view of quantum biology" was just published in Frontiers in Physiology (available to read on our Publications page). Keep up the excellent work!
Wendy was the invited speaker today for the NIH National Center for Advancing Translational Sciences (NCATS) Quantum Information Sciences (QIS) and Quantum Sensing in Biology (QSB) Scientific Interest Group Seminar series. We are getting the word out about Quantum Biology!
The Beane lab welcomes Mattawan High School's AP Biology students who will visit the lab today for a "Planarian Regeneration" research demo.
This week graduate student Samantha Hack will be presenting at Cell Bio 2023: the Joint Meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO) in Boston, MA. Sam will be presenting a poster on her planar cell polarity (PCP) and organ scaling project, as well as giving a selected talk on Uncovering the Relationship Between Bioelectric Signaling and Reactive Oxygen Species (ROS) Accumulation During Adult Tissue Repair. Way to go, Sam!
The Beane lab welcomes the 8th grade students from Portage Northern High, who visited the lab as part of WMU's Science Education Visit Day!
Wendy gave another virtual talk today on Manipulating Tissue Repair with Weak Magnetic Fields as part of the Guy Foundation 2023 Autumn Lecture Series: Quantum Biology and Space Health Programme.
At a combined meeting of Cancer Research UK (CRUK) and The Guy Foundation (London, UK), Wendy gave a virtual presentation on Introduction to Weak Magnetic Fields and Stem Cell Growth.
Wendy gave a virtual talk today at Central Connecticut State University on Development During Adulthood: Using Planarians to Understand Tissue Repair.
Please help us welcome our newest lab members, undergraduate students Dylan Schafer and Lizzie Ruch. Welcome to the Beane nation!
Please join us this Friday from 11:30 am – 1:30 pm in the Haenicke Atrium for the BIORETS Poster Session, and help support Plainwell High School science instructor (and newest #BeaneNation member) Nick Grabemeyer present the results of his summer research in our lab.
Graduate students Samantha Hack and Rae Daun Miller will each be presenting posters at the 82nd Annual Society for Developmental Biology Meeting in Chicago. Have a wonderful time at the conference!
Graduate students Rae Daun Miller and Jana Vučković, along with Dr. Luke Kinsey, gave a teaching demo "Pluripotency in Planaria" today for the 2023 cohort of WMU BIORETS middle and high school science teachers. Great work spreading the news about the awesome regenerative powers of the planarian flatworm!
Wendy gave a virtual talk today via the Big Quantum Meeting link for QuEBS 2023 (Quantum Effects in Biological Systems Workshops) at the University of Surrey, UK.
Help us celebrate Dr. Luke Kinsey who just successfully defended his dissertation! Luke has gotten a position as visiting faculty at Kalamazoo College, where he starts this Fall. Congratulations, Dr. Kinsey!
Wendy and graduate student Rae Daun Miller took our planarian STEM outreach (this time focused on photo- and chemotaxis) to the 5th graders at F.C. Reed Middle School in Bridgman, MI.
Today and tomorrow, come watch the Beane nation REPRESENT! at the 41st Annual Kalamazoo Community Medical and Health Sciences Research Day. Technician Pooja Acharya, post-bac Zach McClenny, and graduate student Luke Kinsey will all be presenting (separate) posters, while graduate student Samantha Hack will be giving a talk on her research.
We are pleased to announce the graduation of Zach McClenny, Pooja Acharya, and Isabela Giorgetti de Carvalho who all received their Bachelor of Science degrees at today's commencement! Congratulations to all of today's graduates!
Congratulations to graduate student Luke Kinsey whose first author paper "Weak Magnetic Fields Modulate Superoxide to Control Planarian Regeneration" has been published in the biophysics section of Frontiers in Physics. Please find this article on our publications page!
The lab's latest paper, "Weak magnetic fields alter stem cell–mediated growth," was published in Science Advances today. Congratulations to current graduate students Alanna Van Huizen (first author) and Luke Kinsey, and all contributing members!

